Get ready to seesome of the world’s most iconic landmarks on a South America cruise. From the mysterious heights of Machu Picchu to the jaw-dropping Christ the Redeemer in Rio, this continent is packed with unforgettable sights.
Sail into Buenos Aires, Argentina’s buzzing capital, where tango rhythms fill the air and historic architecture lines every street. In Montevideo, admire the blend of colonial and modern charm, while Santiago impresses with its Andean backdrop and cosmopolitan edge.
With such a rich mix of culture, history and bucket-list landmarks, South America is a dream cruise destination with sights you’ll talk about for years.
Step into another world on an Antarctica cruise from South America – a once-in-a-lifetime adventure to the frozen edge of the Earth. Most voyages depart from Ushuaia, Argentina, the southernmost city in the world, where your journey into the white wilderness begins.
Cross the legendary Drake Passage and arrive in a land of jaw-dropping beauty. Think towering glaciers, bright blue icebergs, and untouched snow-covered landscapes as far as the eye can see. You’ll spot penguin colonies, seals, and maybe even a humpback whale or two, all thriving in this remote and pristine environment.
With climates ranging from tropical coasts to mountain chill, layering is key. Lightweight, breathable clothes are ideal for warmer stops, think shorts, T-shirts, sundresses and swimwear for beach days or dips in the onboard pool.
If your cruise takes you to higher altitudes, such as Cusco for Machu Picchu or Quito in Ecuador, temperatures can drop, so bring a warm fleece, waterproof jacket and sturdy walking shoes for excursions. For Antarctica extensions, you’ll need proper cold-weather gear: insulated boots, thermal base layers, waterproof trousers and a down jacket.
Whether you're chasing culture, wildlife or epic scenery, the best way to explore South America is by cruise – and there are some top cruise lines ready to take you there in style.
Holland America Line is a favourite for South America sailings, offering in-depth itineraries and mid-sized ships which balance comfort with destination-focused cruising. Princess Cruises is another popular choice, with a mix of classic ports like Buenos Aires and Rio de Janeiro, plus the option to extend your trip with land tours.
Looking for luxury? Silversea and Seabourn both offer ultra-luxury small-ship cruises with expert-led shore excursions and immersive Antarctic expeditions.
Experience the breathtaking beauty of South America, where vibrant cities, ancient landmarks, and dramatic coastlines await.
Find out more about South America and take a look at our top articles and guides, below...
Set sail on an unforgettable journey with a South America cruise to Antarctica.
Departing from Ushuaia, Argentina – the world’s southernmost city – these once-in-a-lifetime voyages take you across the Drake Passage to the untouched landscapes of the Antarctic Peninsula. Spot penguins, whales, and towering icebergs as you explore by ship and zodiac.
Cruise to Brazil and experience the vibrant heart of South America in unforgettable style. Most itineraries include iconic cities like Rio de Janeiro, where you can visit Christ the Redeemer, relax on Copacabana Beach, and soak up samba rhythms at every turn.
Some sailings also stop in Salvador, known for its Afro-Brazilian culture and colonial charm, or Ilhabela, a lush island paradise packed with waterfalls and hiking trails.
South America cruises to Ecuador unlock a world of natural wonders and rich cultural heritage. Many itineraries stop in Guayaquil, Ecuador’s vibrant port city, where you can stroll the colourful Malecón 2000 waterfront and explore colonial landmarks in the Las Peñas district.
For wildlife lovers, Ecuador is the gateway to the legendary Galápagos Islands – a UNESCO-listed archipelago packed with giant tortoises, marine iguanas, and some of the world’s most unique ecosystems.
Cruises to Argentina showcase the best of South America. Most itineraries call at Buenos Aires, the country’s bustling capital. Here, you can watch a live tango show and explore colourful neighbourhoods like La Boca.
Further south, some cruises sail to Puerto Madryn, a hotspot for wildlife lovers where you might spot penguins, whales, and sea lions.
Voyages to Chile offer a stunning mix of wild landscapes, vibrant cities, and unforgettable natural wonders. Many itineraries visit Valparaíso, a colourful coastal city known for its steep hills, funiculars, and incredible street art, and nearby Santiago, Chile’s lively capital set against a backdrop of the Andes.
Further south, cruises sail through Patagonia, calling at ports like Puerto Montt and Punta Arenas, where snow-capped peaks, fjords, and glaciers steal the show.
Peru is one of South America’s most fascinating countries, rich in history, culture, and ancient wonders. Most cruise itineraries stop in Callao, the port for Lima, where you can explore colonial architecture and world-class cuisine.
For many, Peru is the starting point for an unforgettable overland journey to Machu Picchu, the legendary Inca citadel set high in the Andes. Combine your cruise with a land tour to Cusco and the Sacred Valley, and you’ll experience some of the continent’s most iconic sights.