If you are prepared to go "upmarket" and pay the price, the majority of the most expensive ships (while not advertised as child free,) will be so in practice. We have had good child free times on Regent Seven Seas and Seabourn, as there are no child facilities provided!Yes, I AM a miserable old so and so who doesnt like her treasured holidays ruined by other peoples out of control children, -----before someone complains about me and my kind!!!
All the SAGA ships are adult only - SAGA Rose, SAGA Ruby, Spirit of Adventure and (in 2009) Quest for Adventure.
I believe the Calypso in the Thomson fleet is Adults only.